Scleroderma Renal Crisis (SRC): Hypertensive, Normotensive

Scleroderma Renal Crisis in a Normotensive Patient

INTRODUCTION S ystemic sclerosis (scleroderma) is an autoimmune disorder of unclear etiology that leads to fibrosis and vascular injury of the skin and multiple organs, including the lungs, heart, gastrointestinal tract, kidneys, and the musculoskeletal system. It is classified as either diffuse or limited cutaneous based on the extent of skin thickening. In the diffuse form of systemic scleros...

Scleroderma Renal Crisis

Scleroderma renal crisis (SRC) is an infrequent complication of a rare disease. To date, many aspects of the pathophysiology of SRC are still mysterious. Since SRC biopsies are not frequently encountered in practice, our understanding of the spectrum of histologic changes is derived from a combination of a limited personal experience and data obtained from several relatively small pathologic st...

Intriguing presentation of scleroderma renal crisis (scleroderma renal crisis sine scleroderma sine hypertension).

Key words: systemic sclerosis; scleroderma renal crisis; to complain of arthralgia affecting mainly her wrists sine scleroderma; sine hypertension and small joints of the hands. For the last several months she had experienced difficulty in swallowing and anorexia with a resultant weight loss of 20 kg. Despite these symptoms, she did not seek medical

Scleroderma hypertensive renal crisis and the changing pattern of mortality in systemic sclerosis (scleroderma)

Renal complications and scleroderma renal crisis.

Scleroderma renal crisis (SRC) occurs in 5-10% of SSc patients, who may present with an abrupt onset of hypertension, acute renal failure, headaches, fevers, malaise, hypertensive retinopathy, encephalopathy and pulmonary oedema. Patients at greatest risk of developing SRC are those with diffuse cutaneous or rapidly progressive forms of SSc, and treatment with a recently commenced high dose of ...